Liver supplements are rich with the vitamins, minerals, and antioxidants that your liver needs to maintain optimal health and proper function. Liver disease is a risk that many people face, and dangerous toxins can cause permanent damage that leaves behind scar tissue and can even result in liver failure. 1 2 Liver supplements can complement a healthy diet and exercise routine to revitalize your liver, improve your overall health, and potentially reverse liver damage.
We reviewed dozens of liver supplements and have identified the best around to promote your liver’s overall health and wellbeing. As we thoroughly examined each and every liver supplement we came across we considered factors such as ingredient selection, purity, and concentration to choose our top picks, and then we compiled a detailed list of more of our favorites to give you a quick look at the other great liver supplements on the market.
After looking at many different liver supplements, we have chosen the Natures Craft Best Liver Supplement as our overall top pick. This proprietary blend of herbs and minerals features a solid dose of high-quality milk thistle that is bolstered by a plethora of other beneficial ingredients.
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The 5 Top-Rated Liver Supplements
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*Ratings are from Amazon at the time of publication and can change
Best Liver Supplement Overall: Natures Craft Best Liver Supplement
Blending together an assortment of beneficial herbs and minerals, the Natures Craft Best Liver Supplement boasts a hearty helping of high-quality milk thistle extract that is complemented by a suite of supportive nutrients. This supplement’s all-star ingredient is the 200mg serving of pure silymarin marianum milk thistle extract, an herb that has historically been used and thought to improve liver function and prevent liver damage by an overabundance of toxins. However, the current research has been mixed and more larger studies are needed to confirm if milk thistle significantly impacts liver health. 3
Though there are many milk thistle supplements on the market, this blend includes a host of other liver-benefitting herbs such as dandelion, chanca piedra, artichoke, chicory, and many more. And going one, if not two steps further, the blend also includes other vital antioxidants and anti-inflammatory agents that support your liver by delivering health and wellness to your entire body. 4 5 This supplement is like an all-in-one whole-body supplement that emphasizes liver health while feeding essential nutrients to your whole being.
These vegetarian-friendly capsules were made in the USA using all-natural, non-GMO ingredients. In combination with regular exercise and a balanced diet, this supplement promotes better liver function, more energy, mental clarity, a healthy complexion, and a stronger immune system.
Natures Craft Best Liver Supplement Key Features:
- 23-ingredient blend
- Pure silymarin marianum milk thistle extract
- Vegetarian friendly
- Made in the USA
Best Milk Thistle Liver Supplement: NatureBell Milk Thistle Extract
For those who simply want a pure milk thistle supplement, the NatureBell Milk Thistle Extract is one to consider. A highlight of this milk thistle supplement is its high potency of 85% silymarin flavonoids which is the highest concentration we’ve seen. Silymarin is a flavonoid complex unique to milk thistle that is the plant’s element in protecting and cleansing the liver. Some animal research shows that silymarin may reduce liver injury caused by certain toxins. It has also been used to treat certain forms of liver disease. 6 7
The silymarin flavonoids may have a positive effect on reducing free radical damage, certain liver disorders and cancers. 8 9 The compound increases glutathione in the liver which heightens the organ’s own capacity for detoxification. 10 Overall, more research and larger studies are needed to confirm these findings. This supplement is a 30:1 concentrated extract. This means that the 300mg serving size is, in essence, a raw milk thistle herbal equivalent of 9000mg per serving.
As a pure milk thistle supplement encased in a rice flour capsule, this is vegetarian product (it does contain gelatin). It’s also GMO-free and preservative-free. The product is made in the USA and lab tested by a third party to ensure its purity.
NatureBell Milk Thistle Extract Key Features:
- 85% Silymarin flavonoids
- 30:1 extract concentration
- No soy, non-GMO, no gluten, no dairy
- Made in the USA
Best Budget Liver Supplement: Teraputics Milk Thistle
The Teraputics Milk Thistle supplement is nearly identical to our Best Milk Thistle Liver Supplement pick, but it is available at a much lower price. This supplement is organic, vegan, and made in the USA. The sole caveat is that this supplement does not have as high of an extract concentration, but that does not mean that you will be short on milk thistle.
This supplement bottle contains 60 individual vegan-friendly capsules that are each loaded with 500mg of organic milk thistle seed at a 4:1 concentrated extract of silymarin marianum. This provides a raw milk thistle herbal equivalent of 2000mg per serving. While this is certainly less per serving than what you would get with the NatureBell supplement, you could consume more capsules to achieve the same benefits if you so desire.
But that’s only if you want to consume 9000mg of milk thistle, which is much more than most people need. A benefit of this lower dose supplement is that you can better modulate exactly how much milk thistle you are consuming and better identify the correct amount for your body.
Teraputics Milk Thistle Key Features:
- Organic milk thistle seed
- 4:1 extract concentration
- Vegan
- Made in the USA
Best Grass Fed Beef Liver Supplement: Ancestral Supplements Grass Fed Beef Liver
Once a trade secret of the elite bodybuilding community, beef liver supplements like the Ancestral Supplements Grass Fed Beef Liver supplement are now making headway as a popular health and fitness supplement for the masses. This supplement is made purely of 100% nutrient-dense bovine liver from cattle that were pasture-raised in New Zealand where they were grass fed and kept free of hormones, GMOs, and pesticides.
The beef livers have been freeze-dried and ground into a fine dust that is stored in 500mg doses inside each gelatin capsule. The freeze-drying process preserves the biological activity and nutrients of the desiccated livers. Bovine livers are known to hold a large number of vital nutrients for the body, and specifically for liver health, which includes but is not limited to vitamins A, zinc, copper, B12, choline, folate and heme iron. 11 This is one potent pill.
Beef liver is a whole food supplement that can be an integral part of a healthy lifestyle and fits within the molds of the paleo, primal, and ketogenic diets. Each 3000mg serving of this bovine supplement is nutritionally dense with 2.1g protein, 1g fat, 5099 IU vitamin A, 13.6mcg vitamin B12, and 120mg of choline. All of this works together to promote total body health including optimal liver and heart health.
Ancestral Supplements Grass Fed Beef Liver Key Features:
- Single-ingredient bovine liver supplement
- Pasture-raised in New Zealand
- Paleo, primal, and ketogenic diet-friendly
- Hormone, GMO, and pesticide-free
Best Liquid Liver Supplement: Liver Edge Organic Liquid Drops
The Liver Edge Organic Liquid Drops feature many of the same herbal ingredients you’ll find in our top overall pick, as well as many other great liver supplements, but here they are presented in a fast-absorbing liquid form that is ideal for those who have trouble swallowing capsules or simply prefer a liquid solution. Either way, this is a great blend of ingredients in a convenient package.
This liquid supplement has a proprietary blend of ingredients designed to enable the liver to naturally cleanse and detox itself. The formula includes milk thistle seed, dandelion root, chicory root, turmeric root, artichoke leaf, gentian root, and wormwood leaf. The exact amounts of each are not disclosed, but the company offers a 100% money-back guarantee if you are unsatisfied with the product, even if you’ve emptied the entire bottle.
We like the ingredients this product uses, and appreciate that they are organic and GMO-free. Users have mentioned that this product is a great value, and they’ve reported improvements in their blood work data while taking this supplement as a part of their journey toward better health.
Liver Edge Organic Liquid Drops Key Features:
- Seven-ingredient proprietary blend
- Fast-absorbing
- Third-party tested for purity
- Made in the USA
Who Should Buy a Liver Supplement
Liver supplements promote optimal liver function and health. You can take a liver supplement to complement a balanced diet to ensure that you are consuming the ideal amount of vitamins, minerals, and antioxidants that your liver and overall body need.
User reports have shown that liver supplements, in conjunction with increased exercise, a balanced diet, and a reduction in consumed toxins, can prevent and in rare cases even reverse liver disease. The best liver supplements supply your body with essential nutrients that, when taken in moderation, can certainly increase your overall health and wellbeing. Nutritionist Amanda A. Kostro Miller discusses these tips and more in her guide on How to Keep Your Liver Healthy.
You should always consult with your doctor before taking a liver supplement or adding any supplement to your health regimen. To help you find more quality supplements we have reviewed many other products and identified the best magnesium supplements, fiber supplements, prostate supplements, and testosterone boosters for your consideration.
Important Features to Consider
There are a few important considerations to think through before purchasing a liver supplement.
- Herbal or animal. This may be an obvious decision to some, but for those of you who have no preference between the two, there is much to consider. Herbal liver supplements include a select amount of plant-based ingredients (milk thistle is almost always a featured ingredient) that promote your liver’s health by increasing antioxidant absorption, acting as an anti-inflammatory agent, enhancing protein synthesis, and more. 12 Animal-based supplements almost exclusively feature beef liver as the sole ingredient and often feature it as the main ingredient when combined with others. The animal approach is more nutrient-dense than the herbal approach as the beef liver supplements are packed with many more essential vitamins, antioxidants, and minerals like heme iron. Beef liver supplements promote whole-body health, but also contain a dense list of nutrients that the liver itself certainly needs to function optimally.
- Ingredients. The ingredients matter. Milk thistle and pure beef liver are the two primary ingredients you will find featured in liver supplements because they have the most proven benefits that have been backed by decades of use and scientific research. Other ingredients may also provide liver or whole-body benefits, but their results may vary. Be sure to note every ingredient involved in any supplement you take and discuss it with your doctor to avoid overdosing, toxicity or allergic reaction.
- Dosage. Supplements are not regulated by the FDA, and as a result, these supplements can have wildly different concentrations and recommended serving sizes even when they are offering what is essentially the same product. It would be wise to check the dosage of multiple supplements that advertise similar ingredients and effects and compare their results against user reviews and any scientific data available about the correct dosage of a certain ingredient.
- Concentrated extract. While many different ingredients may come from extracts and have different levels of concentration, one ingredient that particularly varies in concentration from product to product is milk thistle. You will find that some supplements advertise 4:1, 30:1, and 50:1 concentrates of milk thistle, effectively multiplying the concentration, and thereby dosage of, the milk thistle in the product. Some milk thistle supplements are not concentrated, and so they have a much more mild dosage per capsule. While milk thistle is generally tolerated, some people may experience gut side effects. There have been reports of allergic reactions to milk thistle, especially in people who are allergic to ragweed, marigold and daisy. 13 Taking supplements while pregnant is not advised unless they are recommended by a healthcare professional. Be aware if you purchase a concentrated form of any supplement so that you know how much you are actually consuming.
- Cleanses and detox. Don’t let these terms fool you as they are simply marketing speak. There is no liver capsule or tincture that will cleanse or detox your liver. The supplements can provide the nutrients your liver needs for it to heal and clean itself, but the only way to truly cleanse your liver is to stop consuming toxins (such as alcohol, tobacco smoke, and high-sodium preserved foods) that overwork and damage your liver. 14 15
Frequently Asked Questions
What are liver supplements and how do they work?
Livers supplements are single-ingredient or multi-ingredient supplements formulated to promote the health and wellbeing of your liver. Milk thistle is a common ingredient in herbal liver supplements. The current research has been mixed and more larger studies are needed to confirm if milk thistle significantly impacts liver health. 16 Other common herbal ingredients in liver supplements included dandelion root, artichoke, and chanca piedra.
Alternatively, grass-fed beef liver supplements are another popular liver-supporting supplement that takes an entirely different approach to liver and whole-body health. Beef liver supplements are usually 100% freeze-dried beef liver powders that are rich with vital nutrients such as antioxidants, vitamins, minerals, and heme iron. Beef liver supplements are thought to increase liver function and promote health throughout the entire body by providing a wealth of essential nutrients that many people lack. 17
Can taking too many supplements damage your liver?
Yes. Be sure to follow the serving suggestion guidelines on whatever supplement you consume, and always consult with your doctor when adding new medications or supplements to your diet.
What supplements are bad for your liver?
Your liver removes toxins from your body. Whenever you consume toxins or overload your body with more vitamins, minerals, and supplements than your body needs you are putting your liver at risk because it must work hard to filter out all of the materials that your body does not need.
There are some substances that have been shown to increase the risk of liver toxicity such as vitamin A and niacin when taken in large amounts. 18 Other possible liver-damaging culprits include ashwagandha and kava. 19 20 Most of these ‘bad’ results are an effect of too much of these substances in the body that the liver then has to process. Always talk to your doctor before taking any supplements, even if they’re over-the-counter.
What vitamins are good for your liver?
A healthy diet, healthy weight, and exercise patterns all benefit your liver health. As far as micronutrients, it’s best to get most of your vitamins and minerals via food. While supplements can help bring balance to your system when it is lacking, they can also overload your body when taken with too much gusto. The best way to know what vitamins your body needs is to talk to your doctor and have bloodwork done to determine your actual nutrient levels.
Other Liver Supplements We Reviewed
We looked at 20 other liver supplements. Even though they didn’t make our five best liver supplement list, they’re the best of the rest and each is still a great option for supporting your liver’s health. The information you’ll need to compare each one is included with the listing.
- Capsule Liver Supplements
- Liquid Liver Supplements
- Grass Fed Beef Liver Supplements
- Milk Thistle Liver Supplements
- Budget Liver Supplements
Capsule Liver Supplements
Dr. Christopher’s Original Formula
Dr. Christopher’s Original Formula is a liver and gallbladder supplement that is made from a proprietary blend of barberry bark, wild yam root, cramp bark, fennel seed, ginger root, catnip herb, and peppermint leaf. Users have reported marked improvements in the health and function of the livers and gallbladders with regular use of this supplement.
Key Features:
- Liver and gallbladder support
- Proprietary formula
- 100 capsules
Cost: $20
Comprised of 22 active ingredients, the Herba Heal Liver Cleanse is more like a targeted multivitamin than a standalone supplement. A wealth of vitamins and herbs are blended with common liver supporting ingredients including milk thistle for a focused approach to overall wellness.
Key Features:
- 22 active ingredients
- Includes milk thistle
- Made in the USA
Cost: $20
Naturenetics LiverSmart is a proprietary blend featuring milk thistle extract that is blended with dandelion root extract, artichoke leaf extract, yellow dock root, protease, and beet root. This antioxidant-rich blend is manufactured in Oregon, USA and has been independently lab tested for purity.
Key Features:
- 6 active ingredients
- Independent lab tested formula
- Made in the USA
Cost: $25
TUDCA Liver Support Supplement
Taking a different approach to liver health, the TUDCA Liver Support Supplement is a 100% tauroursodeoxycholic acid supplement. This is a naturally occurring bile acid in the human body. FDA-approved TUDCA treatments have shown to help treat cholestatic liver disease, reducing cellular stress and much more. 21 22
Key Features:
- TUDCA ingredient backed by some research in liver and non-liver diseases
- Promotes health liver enzymes
- Made in the USA
Liquid Liver Supplements
Fairmile Organics Liver Cleanse
Comprised of a plant-based formula that includes peppermint, milk thistle, dandelion root, chanca piedra, and chicory root, Fairmile Organics Liver Cleanse is full of natural antioxidants and vitamins that have been brought together to cleanse your liver. The liquid formulation absorbs fast.
Key Features:
- Five ingredient blend
- 14 day supply
- Made in the USA
Cost: $25
Maui Herbs Liver Cleanse Tincture
The Maui Herbs Liver Cleanse Tincture has 84 servings of its five ingredient blend. Milk thistle, chanca piedra, turmeric root, dandelion root, and artichoke are the active ingredients. Ingredients such as milk thistle and turmeric act as an anti-inflammatory, and boost the immune system. 23 24 25
Key Features:
- Five ingredient blend
- Certified organic
- Made in the USA
Cost: $20
The five ingredients that make up the VitaLiver Health Cleanse are milk thistle, dandelion root, chanca piedra, angelica, dandelion, and artichoke. This blend promotes overall health and wellness while specifically protecting and defending the liver.
Key Features:
- Five ingredient blend
- 48 servings
- Made in the USA
Grass Fed Beef Liver Supplements
Ancestral Supplements Grass Fed Beef Organs
A sister product to our top grass-fed liver supplement pick, the Ancestral Supplements Grass Fed Beef Organs supplement is made from a blend of multiple beef organs that promote full-body health, including the liver. In each serving, there are 600mg each of grass-fed beef liver, heart, kidney, pancreas, and spleen.
Key Features:
- Five ingredient blend
- 30 servings
- Pasture-raised in New Zealand
Cost: $45
Beverly International Desiccated Liver Tablets
Beverly International Desiccated Liver Tablets are made from 100% grade 1 beef liver and supply 300mcg vitamin B-12 per serving. These tablets are used by bodybuilders to complement their intense workout plans.
Key Features:
- B-12 loaded
- 100% grade 1 beef liver
- Pasture-raised in Argentina
Cost: $40
Enviromedica Freeze Dried Beef Liver
You could say there’s no supplement purer than the Enviromedia Freeze Dried Beef Liver supplement. The sole ingredient is freeze-dried New Zealand bovine liver, and the capsule casing is made from gelatin. No fillers, sweeteners, or artificial anything. This one ingredient is abundant in vitamins and minerals that are essential to a healthy liver and the rest of your body. 26
Key Features:
- Independently lab tested
- Single-ingredient supplement with gelatin casing
- Pasture-raised in New Zealand
Cost: $30
Like other pure beef liver supplements, the Flyby Grass-Fed Beef Liver capsules provide pure undefatted beef liver that is packed with amino acids, vitamins, minerals, and iron. The cattle that were used to make this supplement were pasture-raised in Argentina, and the pills are lab-tested to ensure that they are hormone, pesticide, and GMO-free.
Key Features:
- 180 capsules
- Pasture-raised in Argentina
- One-year money-back guarantee
Cost: $20
Wholesome Wellness Beef Liver Capsules
Manufactured in the USA from cows that were pasture-raised in New Zealand and then distributed from Portland, Oregon, the Wholesome Wellness Beef Liver Capsules are fully traceable and have been third-party lab-tested to ensure purity.
Key Features:
- Contains choline
- Two grams of protein per serving
- Pasture-raised in New Zealand
Milk Thistle Liver Supplements
FarmHaven Milk Thistle Capsules
FarmHaven Milk Thistle Capsules are comprised of a 30:1 milk thistle seed extract providing 375mg per serving and 120 capsules per bottle. This vegan product is made with veggie capsules for those who adhere to that style of diet.
Key Features:
- 80% standardized silymarin
- 30:1 concentrated extract
- 375mg per serving
Cost: $22
Fresh Nutrition Milk Thistle claims to be the strongest available milk thistle supplement on Amazon, and with a loaded 2000mg at 4:1 extract per serving inside of each and every capsule, it is certainly up near the top. This supplement is certified organic and its ingredients can be traced all the way back to their source.
Key Features:
- 80% silymarin
- Certified organic
- 2000mg per serving
Cost: $16
The Pure Co Milk Thistle is a powerful supplement with 300mg per capsule with a 30:1 extract composition that makes each serving a 9000mg herbal equivalent. This product is made with organic ingredients and vegan.
Key Features:
- 80% silymarin
- 30:1 concentrated extract
- 300mg per serving
Cost: $16
The Superior Labs Milk Thistle capsules contain 250mg of pure milk thistle at a 4:1 extract. Each batch of this supplement is tested by third-party labs for purity. The capsules are manufactured in the USA in an FDA-approved facility.
Key Features:
- 80% silymarin
- 4:1 concentrated extract
- 250mg per serving
Budget Liver Supplements
The Natures Wellness Milk Thistle supplement appears to be a single-ingredient supplement at first glance, but it has two active ingredients and several other inactive ingredients. There are 525mg 80% silymarin milk thistle seed extract per serving and 825mg milk thistle seed powder per serving.
Key Features:
- Two active ingredient blend
- Made in the USA
- Lifetime money-back guarantee
Cost: $13
PurePremium Supplements Milk Thistle
This PurePremium Supplements Milk Thistle is a two active ingredient blend like the last product we listed, but this one has a lower concentration of those ingredients. Here, there are 175mg 80% silymarin milk thistle seed extract per serving and 275mg milk thistle seed powder per serving.
Key Features:
- Two active ingredient blend
- Formulated in the USA
- 120 tablets
Cost: $15
These Toniiq Milk Thistle Capsules have stunning stats for being such an affordable product. The single-ingredient capsules are packed with 500mg of 80% flavonoids of organic milk thistle at a 50:1 concentrate. The vegetable capsules are made from organic rice. For a budget-friendly pure milk thistle supplement, it doesn’t get much better than this.
Key Features:
- Single-ingredient product
- 50:1 concentrate
- 500mg per serving
Cost: $15
Coin-conscious consumers who want a multifaceted liver supplement should definitely consider the Wiseceutical Liver Support supplement. This product combines two common liver supporting ingredients, milk thistle and dandelion, and combines them with BioPerine for enhanced bioavailability. 27 28 This is a great triple-threat supplement that will support your liver’s health. Overall, more human research is needed to confirm the beneficial effects of these ingredients on liver health.
Key Features:
- Three-ingredient blend
- 5:1 concentrated milk thistle
- BioPerine added for enhanced bioavailability
Cost: $15
Article Sources
Healing Daily uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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