The Best Nootropic Supplements

When you find it difficult to focus on your daily tasks or remember information you need or memories you love, it can feel like your brain is the enemy. The good news is, there are things you can do to improve your situation. You can find nootropic supplements that include boosters for your brain, giving it the specific nutrients it needs to maximize its functionality. If you’re not sure what to look for in a nootropic supplement, though, don’t panic – we’ve done the homework for you.

We reviewed dozens of nootropic supplements to identify the best of the best. We looked at nootropic supplements that will keep you calm and focused and those that will keep your mind sharp as a whip. We looked for the yummy gummy nootropic supplements as well as those with an extra boost of caffeine to make sure your energy doesn’t slow you down any, either. No matter what you’re looking for in a nootropic, we have the right one for you.

Best Nootropic Supplement Overall
Brain Powher

A proprietary blend of powerful brain-boosting ingredients, Brain Powher is the best nootropic supplement you can buy.

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It was clear from nearly the beginning of your research that when it came to nootropics, one product stood out among its peers. Brain Powher offers a proprietary blend of a variety of brain-boosting ingredients to unlock your full cognitive potential.

The 5 Top-Rated Nootropic Supplements

Editor's PicksBrandRating
Best Nootropic Supplement OverallPowher Brain PowherN/A
Best Nootropic Supplement Runner UpNeurohacker Collective - Qualia Mind4.2
Best Budget Nootropic SupplementNutritional Essentials Nootropic Brain Function Booster Supplement4.1
Best CBD Nootropic SupplementSunday Scaries CBD Energy Shot4.9
Best Nootropic Supplement with CaffeineGenuis Brand Genius Consciousness4.3

*Ratings are from Amazon at the time of publication and can change

Best Nootropic Supplement Overall: Brain Powher

The Brain Powher contains a nootropic formula that’s built around ingredients approved by health safety authorities like EFSA. For example, it contains a 3g daily serving of Glucomannan, which has recently been approved as a source of dietary fiber by the FDA. According to the FDA, “Dietary fiber that can be declared on the Nutrition and Supplement Facts labels includes certain naturally occurring fibers that are ‘intrinsic and intact’ in plants and added isolated or synthetic non-digestible soluble and insoluble carbohydrates that FDA has determined have physiological effects that benefit human health.”

Brain Powher also includes choline, which supports normal fat metabolism, and chloride, which supports normal digestion, as well as vitamin B12, which reduces tiredness and fatigue. The proprietary blend also includes plant extracts and other natural ingredients used by practitioners of traditional medicine for hundreds of years to boost mental clarity and performance, as well as minerals to help prevent deficiencies that have been linked to low mood.

Brain Powher Key Features:

  • Includes Ashwagandha extract, gingko bilboa extract, lion’s mane mushroom, magnesium, niacin, thiamine, and bacopa monnieri extract
  • 2 capsules per serving
  • 60 capsules per bottle

Our Runner Up Pick: Neurohacker Collective – Qualia Mind

Runner Up
Neurohacker Collective - Qualia Mind Essentials

An effective nootropic supplement, Qualia Mind Essentials boasts brain-boosting benefits.

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The Neurohacker Collective – Qualia Mind includes various brain function-boosting ingredients, such as Phosphatidylserine, which studies suggest it may aid memory. In addition to this, there’s also organic coffeeberry – which contains caffeine and has brain-boosting benefits.

Of course, you don’t have to take just our word for it – there’s plenty singing its praises online. It has nearly 400 customer reviews and impressive overall ratings! That means your chances of satisfaction are definitely better than average.

Neurohacker Collective – Qualia Mind Key Features:

  • Non-GMO, gluten-free and vegan
  • 154 servings per bottle
  • 100 day money back guarantee

Best Budget Nootropic Supplement: Nutritional Essentials Nootropic Brain Function Booster Supplement

Best Budget Nootropic Supplement
Nutritional Essentials Nootropic Brain Function Booster Supplement
For a nootropic that won’t have you worried about the money you need to invest in it, check out the Nutritional Essentials Nootropic Brain Function Booster Supplement.

The Nutritional Essentials Nootropic Brain Function Booster Supplement is made with a strong and potent formula to support focus, memory, and brain clarity by using a blend of St. John’s Wort, gingko bilboa, L-glutamine, bacopa monnier leaf, and more. The combination of these ingredients can help improve your mood and stress level, as well as clear your brain of fogginess and allow you to focus like never before.

On Amazon, you can find this nootropic supplement with an overall rating of 4.1 stars with over 4,000 customer reviews. While every part of the features above makes this a tempting product, the component that will convince you to purchase is very likely the cost. You can get a 1-month supply of this memory-boosting supplement for under $10 – a total steal!

It is worth mentioning that the primary ingredient, St. John’s Wort, has been known to interfere with other medications, so it’s important to check with your doctor before starting this supplement.

Nutritional Essentials Nootropic Brain Function Booster Supplement Key Features:

  • 100% satisfaction guarantee
  • 2 capsules per serving
  • 30-day supply

Best CBD Nootropic Supplement: Sunday Scaries CBD Energy Shot

Best CBD Nootropic Supplement
Sunday Scaries CBD Energy Shot

If you want to make sure your brain is focused and avoiding common anxieties (or “Sunday Scaries”) then you won’t want to miss Sunday Scaries CBD Energy Shot.

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The Sunday Scaries CBD Energy Shot is perfect for the brain clutter that is often felt with anxiety. If that’s something you struggle with, then you’ll love the effect the CBD has on your mood. Not only can anxiety ease with a regular dose of CBD, but it may also improve depression. With CBD’s involvement in your body’s endocannabinoid system, taking this shot may very well have your mental state in a better place than it’s ever been.

The B vitamins included in these energy shots will give you a boost to clear your brain from any sleepiness, and brain fog, as well. There’s also caffeine from organic coffee beans, too, so you’ll actually feel plenty of energy after this shot.

You can try it at a regular price to begin and if you decide you absolutely love it and want to pick it up every month, then they have a Subscribe & Save option that will let you get it automatically shipped to your front door without needing to stress about running out.

Sunday Scaries CBD Energy Shot Key Features:

  • Includes ginseng, guarana, B vitamins, taurine, and more
  • 2 packaging options
  • 3 flavors available

Best Nootropic Supplement with Caffeine: Genuis Brand Genius Consciousness

Best Nootropic Supplement with Caffeine
Genuis Brand Genius Consciousness
If you want a nootropic with the support of a bit of extra caffeine, then you should consider the Genuis Brand Genius Consciousness.

The Genuis Brand Genius Consciousness comes from a brand that made its name on knowing the best ingredients for your brain and blending them in a way that makes for the best formula available. The label has 100% transparency, so you won’t need to wonder what you’re putting into your body, like with other brand’s proprietary blends. Among the uniquely chosen, specialized ingredients this powder includes is L-Alpha glycerylphosphorylcholine (or Alpha-GPC), a naturally occurring compound found in your brain that has been shown to give a therapeutic role in cognitive recovery.

It also includes a boost of caffeine in the form of 100 mg per serving, so you’ll have that boost to your alertness to make sure you’re supporting your mind in every way you can to clear the fog and sleepiness. There are nearly 10,000 customer reviews on Amazon for this product with an overall rating of 4.3 stars.

Genuis Brand Genius Consciousness Key Features:

  • Watermelon flavor
  • 15 servings per container
  • Contains caffeine, do not take within 6 hours of bed

Who Should Buy a Nootropic Supplement

If you’re struggling with your memory or focus, a nootropic supplement could be the answer you didn’t know you were looking for. Whether you struggle with sleep deprivation or attention problems, there are plenty of natural and stimulant supplements that can provide you support to your brain function. New moms who get the bare minimum of sleep, or college kids studying for a big exam – the proper nootropic can make sure they’re on top of what they need to be so that they’re not falling behind or letting anyone down. If you have been diagnosed with an attention problem, but you’re not comfortable with the prescription medications, you may want to try a nootropic. We definitely don’t recommend disregarding medical advice; check with your doctor, of course. But the right nootropic may just help you focus like never before.

For those of us who are aging and struggling to keep each bit of knowledge we’ve accumulated over our lives, a bit of a boost can certainly come in handy. If each brain is like an iceberg and each piece of information you learn is a penguin, just as the iceberg can only hold so many penguins before some start falling off, your brain is only capable of having so many bits of knowledge readily accessible to you. A good nootropic can give the penguins a boat, or even expand your iceberg!

If you have an occasional problem and are looking for other ways to clear your mind, check out How To Get Rid Of Brain Fog: 10 Tips On How To Clear Brain Fog Quickly.

Best Nootropic Supplement Overall
Brain Powher

A proprietary blend of powerful brain-boosting ingredients, Brain Powher is the best nootropic supplement you can buy.

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Important Features to Consider

A nootropic should have beneficial ingredients that help reduce brain fog and improve mental clarity. Here’s what to consider when selecting a nootropic supplement:

  • Lion’s mane mushrooms. This one ingredient in particular stands out as a quality memory and focus booster. If your memory suffers from the decline of age, then you may especially benefit from the two components found in Lion’s mane mushroom that stimulate the growth of new brain cells. The two compounds are called hericenones and erinacines, and they may even have a preventative function for dementia and Alzheimer’s disease. More research is needed to establish this link conclusively, but in the meantime, it could help you remember why you went into the kitchen.
  • Caffeine. Caffeine doesn’t help your memory, or focus, per se, but it does help you become more alert. Because brain fog is often due to a lack of proper sleep, that caffeine may very well clear the fog. For this reason, it pairs excellently with other ingredients in nootropics.
  • CBD. CBD has a calming effect, so if your anxiety prevents your brain from focusing, that side effect alone may make it well worth including. However, CBD is also believed to have a protective effect on the brain’s cells, which can help maximize your brain’s performance.
  • Minimal side effects. Look for nootropics with the right blend of ingredients to meet your needs. You may want to avoid nootropics containing caffeine if you’re particularly sensitive to it, for instance, or if products containing caffeine have made you feel anxious or jittery in the past. Some nootropics contain other ingredients that help to balance out the jittery effects of caffeine, so fully research any nootropic supplement (and check with your doctor first!) before taking any supplement.

Frequently Asked Questions

What is a nootropic supplement and how does it work?

Nootropic supplements, sometimes referred to as “smart drugs,” are medications and supplements that will enhance your cognitive performance. To be classified as a nootropic, it must provide some protection or resistance to brain injury. For example, the lion’s mane mushroom creates additional brain cell growth and protects your brain from deterioration. They often give you a boost of energy and reduce your anxiety, both of which will allow you to better focus. Memory and focus enhancement are the two effects that you can expect from a nootropic. There are prescription strength and more natural and over the counter supplements, as well.

You will often see the greatest benefit from those struggling with sleep, or those who need to focus for short bursts of time. Taking it before a night to study for a test, or after a long night with a teething baby are excellent examples.

Is caffeine a nootropic?

Though there is some debate on this, typically caffeine is not considered a nootropic. It has negative side effects and is addictive, and both of those generally prohibit it from inclusion as a nootropic. Though the caffeine does give a stimulant that will can help your focus, it may not always have positive side effects. For example, while some people with ADD use coffee to self medicate and focus better, those with anxiety may actually find the caffeine makes them less focused and more anxious. And while caffeine can help in conjunction with other nootropics, bear in mind it can’t offer any cognitive growth or protection. And on its own, it could very well make your focus, anxiety, and sleep to worsen.

Is CBD a nootropic?

Unlike caffeine, CBD can be called a nootropic. While it may not be what you have in mind when you think of a supplement to keep you focused and performing at peak cognitive function, the effect the CBD has on the Endocannabinoid System (ECS) within your body is undeniable. Through this boost to your ECS, your body will better be able to regulate and find a peaceful balance for everything from inflammation, to your mood, to yes, your memory.

Are nootropic supplements bad for you?

As a rule, no. Nootropic supplements generally aren’t bad for you. However, prescription nootropics can have some pretty intense side effects. You may experience a fast heart rate, trouble with vision, high blood pressure, and insomnia, depending on the medication. Always talk your medication options over with your doctor thoroughly before trying new medicines.

If you want to go the more natural route, you may find slightly safer options (though they won’t be as potent, obviously). You can look for CBD and lion’s mane mushrooms, as we’ve mentioned, but also gingko biloba, panax ginseng, bacopa monnieri, rose root, L-theanine,  and omega-3 fatty acids. If you’re concerned about the safety (and even if you’re not) talk to your doctor before starting a new nootropic supplement.

Other Nootropic Supplements We Reviewed

Best Nootropic Supplement Overall
Brain Powher

A proprietary blend of powerful brain-boosting ingredients, Brain Powher is the best nootropic supplement you can buy.

Check Price

We looked at 20 other nootropic supplements. Even though they didn’t make our 5 best nootropics list, they’re the best of the rest and each is still a great option for you. The information you’ll need to compare each one is included with the listing.

Nootropic Supplements to Boost Brain Function

BioSchwartz Nootropic Brain Boost Supplement

BioSchwartz Nootropic Brain Boost Supplement

This nootropic supplement is made to battle stress and support your mood while promoting oxygen flow to the brain.

Key Features:

  • 100% satisfaction guarantee
  • Gluten-free, non-GMO
  • 30 servings

Cost: $20

Focus Factor, Extra Strength Concentration and Brain Focus Supplement

Focus Factor, Extra Strength Concentration and Brain Focus Supplement

You’ll want to take these four tablets with plenty of food and water, and depending on your weight and activity level, you may take up to (but no more) than eight pills a day.

Key Features:

  • 30 servings per container
  • Patented extra-strength formula
  • 4 tablets per serving

Cost: $30

Genius Brand Genius Mindfulness

Genius Brand Genius Mindfulness

This product will give similar effects as our pick for Best Nootropic with Caffeine, but this one is ideal for those of us who prefer caffeine-free.

Key Features:

  • Veggie capsules with ashwagandha, coffee arabica, blueberry blend and more
  • 30 capsules per bottle
  • 1 pill daily

Cost: $35

Huntington Labs Nootropics Brain Supplement

Huntington Labs Nootropics Brain Supplement

Take these veggie capsules approximately thirty minutes before eating one each day and with plenty of water.

Key Features:

  • 2 size options
  • For balanced nutrition; vitamins A, C, B, D, E, Calcium, Iron, and more
  • Proprietary blend of green tea extract, bacopa extract, bilberry fruit extract, and more

Cost: $15

Maui Herbs Brain Support

Maui Herbs Brain Support

With 1400 mg of natural herbal supplements, like ginkgo Biloba, Panax ginseng, ashwagandha root, and more, this is one alternative to prescription nootropics that you’ll love.

Key Features:

  • 2 capsules per serving
  • 100 capsules
  • Non-GMO

Cost: $20

MAV Nutrition Nootropics Brain Focus Gummies Supplements for Kids

MAV Nutrition Nootropics Brain Focus Gummies Supplements for Kids

If you’re looking for a little focus support for your kid, then you won’t want to miss this notropic.

Key Features:

  • 2 gummies per serving
  • 60 gummies
  • Includes Omega 3 6 & 9, DHA, COQ10, blueberry extract, and more

Cost: $20

NEURIVA Nootropic Brain Support Supplement

NEURIVA Nootropic Brain Support Supplement

This nootropic claims to fuel six different indications of brain function: learning, memory, focus, reasoning, accuracy, and concentration.

Key Features:

  • Caffeine-free
  • Non-GMO, vegetarian and gluten-free
  • Made with natural ingredients like coffee cherry, phospholipids, and more

Cost: $40

Nooflow Nootropic Brain Booster Supplement

Nooflow Nootropic Brain Booster Supplement

By taking this nootropic, you’ll get plenty of brain support with ingredients like bacopa monnieri, L-theanine, grape seed extract, and more.

Key Features:

  • USA-made
  • 60 capsules
  • 2 capsules per serving

Cost: $25

ONNIT Alpha Brain Instant

ONNIT Alpha Brain Instant

This nootropic is a daily cognitive support supplement that uses earth-grown botanicals to support memory and focus.

Key Features:

  • 3 packaging options; capsules, powder, or stick packs
  • Dairy, gluten, and caffeine-free
  • Includes amino acids and vitamins

Cost: $60

Organixx Ageless Brain

Organixx Ageless Brain

This nootropic uses a proprietary blend of organic ingredients to maximize your brain’s performance.

Key Features:

  • Take with at least 8 oz of water
  • Subscribe & Save options available
  • 30 servings per container

Cost: $60

Orphic Nutrition Neuro Prime Brain Booster Supplement

Orphic Nutrition Neuro Prime Brain Booster Supplement

This nootropic will use the natural effects of herbal extracts, and not stimulants, to keep you energetic and alert.

Key Features:

  • 30 capsules per container
  • Improves mood, energy, mental clarity, and focus
  • Caffeine-free

Cost: $20

P3OM 120 CAPS

P3OM 120 CAPS

If you find yourself pleased with the effect of this product, you can subscribe and save an additional 53% on your next shipment.

Key Features:

  • 120 capsules per container
  • Includes powerful probiotic
  • 1 capsule per serving

Cost: $75

Ruveda Naturals Natural Nootropic Brain Booster

Ruveda Naturals Natural Nootropic Brain Booster

This nootropic is made with plenty of natural ingredients to make sure your brain is as sharp as possible.

Key Features:

  • 60 vegetable capsules per container
  • Includes lion’s mane mushroom, Bacopa Monnieri, Ashwagandha, Ginkgo Biloba and more
  • 2 capsules per serving

Cost: $20

Vital Vitamins Brain Supplement Nootropics Booster

Vital Vitamins Brain Supplement Nootropics Booster

To sharpen your mental clarity naturally, you’ll appreciate the boost of B vitamins in this nootropic.

Key Features:

  • Includes Gingko Biloba, Bacopa Monnieri, and more
  • 30 capsules per container
  • 1 capsule per serving

Cost: $20

Zhou Nutrition Neuro Peak Brain Support Supplement

Zhou Nutrition Neuro Peak Brain Support Supplement

You’ll want to take this nootropic one to two times a day with your meals (or as directed by your doctor).

Key Features:

  • Includes Bacopa Monnieri, Ginkgo Biloba, Vitamin B12, and more
  • 30 capsules per container
  • 1 capsule per serving

Cost: $25

Nootropic Supplements with Caffeine or CBD

Fairmile Organics Brain Supplement

Fairmile Organics Brain Supplement

By adding two drops of this nootropic, under your tongue daily, you’ll likely notice a big change in your mental clarity.

Key Features:

  • 2 oz
  • Proprietary blend of green coffee, ginseng, Ginkgo biloba, and more
  • Refrigerate after opening

Cost: $25

Garden of Life Dr. Formulated Organic Brain Health Memory & Focus

Garden of Life Dr. Formulated Organic Brain Health Memory & Focus

This nootropic features the brain boost of whole coffee fruit, wild blueberry extract, grape extract. and more.

Key Features:

  • Take 2 tablets daily with food
  • 60 vegetarian tablets per container
  • USDA organic, non-GMO

Cost: $25

Joy Organics CBD Energy Drink Mix

Joy Organix CBD Energy Drink Mix

The CBD in this nootropic will give you a relaxed energy boost that will have your mind clear while the caffeine will make sure that it hits fast.

Key Features:

  • 5 servings per box
  • 75 mg caffeine
  • 18-month shelf life

Cost: $20

Nanocraft CBD Rise and Grind Bundle

Nanocraft CBD Rise and Grind Bundle

If you struggle with the morning brain fog, this is a set that will have you clear and focused both in the morning and during the common afternoon slump.

Key Features:

  • Subscribe and Save for 15% off
  • 10mg (CBD oil) & 25mg (powder) CBD per serving
  • 100% THC-free

Cost: $115

Sunday Scaries Dawn To Yawn Plan

Sunday Scaries Dawn To Yawn Plan

This nootropic bundle will give you the focus and clarity you need through every step of your day.

Key Features:

  • Subscribe and Save for 20% off
  • Includes Original Gummies, Vegan Gummies, and CBD tincture
  • Made with broad-spectrum CBD

Cost: $108

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